一、主持 1. 黑龙江省科学基金面上项目,C201444,京尼平苷对LPS诱导小肠黏膜损伤修复作用及相关机制研究,2014/07-2017/07,6万元,已结题,主持 2. 中国博士后科学基金会(第62批面上一等资助),2017M620124,NF-κB对LPS诱导小肠黏膜IAP表达的调控,2017/11-2019/12,8万元,已结题,主持 3. 中国博士后科学基金会(第十一批中国博士后科学基金特别资助),2018T110320,京尼平苷对免疫应激仔猪NF-κB/IAP信号通路的调控研究,2018/06-2021/08,15万元,已结题,主持 4. 兽医学(中医药)北京市重点实验室项目,TCVM-201902,中药复方对围产期奶牛能量负平衡的干预作用及其调控机制,2019/04-2020/04,5万,已结题,主持 5. 中央引导地方科技发展专项项目省科技厅(国家级),ZY18C07-18,“玉鹅种养模式”扶贫示范,2018-2021,15万,已结题,主持 6. 黑龙江省科技计划省院科技合作项目,YS20B04,奶牛围产期中药保健制剂的研发与应用,2020/11-2022/11,20万元,已结题,主持 二、参加 1. 国家自然科学基金青年项目,31101835,基于lktA/hly 的牛坏死杆菌嵌合保护性抗原的筛选,2012/01-2014/12,23万元,已结题,参与 2. 国家自然科学基金面上项目,31172369,非酒精性脂肪肝增量表达CYP2A5的作用机制及其发病机制,2012/1-2015/12 ,62万元,已结题,参与 3. 黑龙江省科学基金面上项目,C2015040,断奶仔猪小肠谷氨酸转运体表达规律及调控机制研究,2015/07-2018/07,10万元,已结题,参与 4. 国家自然科学基金面上项目,31873028,泌乳早期高产奶牛亚临床维生素E缺乏的血清生物标示物筛选与确证,2019/01-2022/12,82万,已结题,参与 5. 国家自然科学基金委员会,面上项目,32072931,TGF-β3介导的凋亡细胞清除障碍对酮病奶牛乳腺TLR4介导的局部天然免疫功能调节作用及分子机制,2021/01/01-2024/12/31,58万元,在研,参与 代表性研究成果和学术奖励情况(影响因子总计45.071) 一、SCI论文 1. Yizhe Cui, Qiuju Wang, Xiaochong Lia, Xiuying Zhang*. Experimental nonalcoholic fatty liver disease in mice leads to cytochrome P450 2a5 upregulation through nuclear factor erythroid 2-like 2 translocation. Redox Biol. 2013 Aug 24;1:433-40. doi: 10.1016/j.redox.2013.08.003. IF(6.325, 5-year IF7.613. (2区) 2. Yizhe Cui, Qiuju Wang, Xing Yi, Xiuying Zhang*. Effects of fatty acids on Cyp2a5 and nrf2 expression in mouse primary hepatocytes. Biochem Genet. 2016 Feb;54(1):29-40. doi: 10.1007/s10528-015-9697-6. IF(1.927), (4区) 3. Yizhe Cui, Rui Sun, Qiuju Wang*, Mengzhu Wang. Hepatotoxicity induced by intragastrically administrated with Gardenia decoction in mice. Nat Prod Res. 2017 Dec;31(23):2824-2827. doi: 10.1080/14786419.2017.1297934.IF(1.928) (4区) 4. Yizhe Cui*†, Qiuju Wang*†, Shengjun Liu*†, Rui Sun, Yaqiang Zhou, Yue Li. Age-Related Variations in Intestinal Microflora of Free-Range and Caged Hens. Front Microbiol. 2017 Jul 11;8:1310. doi: 10.3389/fmicb.2017.01310. IF(4.076) (2区) 5. Yizhe Cui† , Qiuju Wang†, Rui Sun, Li Guo, Mengzhu Wang, Junfeng Jia, Chuang Xu* and Rui Wu*. Astragalus membranaceus (Fisch.) Bunge repairs intestinal mucosal injury induced by LPS in mice. BMC Complement Altern Med. 2018 Aug 3;18(1):230. doi: 10.1186/s12906-018-2298-2.IF(2.109) (2区) 6. Yizhe Cui#, Qiuju Wang#, Mengzhu Wang, Junfeng Jia, Rui Wu*. Gardenia decoction prevent intestinal mucosal injury by inhibiting pro-inflammatory cytokines and NF-κB signaling. Front Pharmacol. 2019 Mar 28;10:180. doi: 10.3389/fphar.2019.00180. eCollection 2019. IF(3.845) (2区) 7. Yizhe Cui,† Qiuju Wang,† Renxu Chang,† Xiaocui Zhou,‡ and Chuang Xu†*. Intestinal barrier function-NAFLD interactions and possible role of gut microbiota. Journal of agricultural and food chemistry. 2019 Mar 13;67(10):2754-2762. doi: 10.1021/acs.jafc.9b00080. IF(5.279)(1区), 2020, 2021年度两次被ESI数据库高倍引。 8. Yizhe Cui1†, Renxu Chang1†, Tao Zhang2†, Xiaocui Zhou3, Qiuju Wang1, Haiyun Gao1, Lintong Hou1, Juan J. Loor4 and Chuang Xu1*. Chinese Herbal Formula (CHF03) attenuates non-alcoholic fatty liver disease (NAFLD) through inhibiting lipogenesis and anti-oxidation mechanisms. Front Pharmacol. 2019 Oct 15;10:1190. doi: 10.3389/fphar.2019.01190. eCollection 2019. IF(3.845) (2区) 9. Yizhe Cui,Qiuju Wang,Renxu Chang,Ahmad Aboraga,Juan J. Loor andChuang Xu. Network pharmacology-based analysis on Pogostemon Cablin (Blanco) Benth alleviates the multi-hit effect on non-alcoholic fatty liver disease in mice. Front Pharmacol. 2021 Nov 24;12:789430. doi: 10.3389/fphar.2021.789430. eCollection 2021. IF(5.810) (2区) 10. Yizhe Cui, Zhuorui Shan, Lintong Hou, Qiuju Wang, Juan J. Loor and Chuang Xu. Effect of natural Chinese herbal supplements (TCMF4) on lactation performance and serum biomarkers in peripartal dairy cows. Front Vet Sci. 2022 Jan 10;8:801418. doi: 10.3389/fvets.2021.801418. eCollection 2021. IF(3.412) (2区) 11. Zhuorui Shan 1, Junfeng Jia 1, Qiuju Wang, Yizhe Cui*. Network pharmacology-based analysis on geniposide, a component of gardenia jasminoides, beneficial effects to alleviate LPS-induced immune stress in piglets. International Immunopharmacology. 2023 Feb 28;117:109894. doi: 10.1016/j.intimp.2023.109894. IF(5.714) (2区) 二、专著 1.崔一喆,王秋菊,动物肝肠炎症中药防控机理与应用,化学工业出版社CIP(2021)第149334号,21万字,2021.7. 2.王秋菊,崔一喆,微生态制剂及其应用,化学工业出版社(2014)第125620号,20万字,2014.08. 3.王秋菊,崔一喆,微生态制剂技术与应用,化学工业出版社(2018)第025975号,2018.05. 4. 王新,崔一喆,抗菌后效应及临床应用,东北林业大学出版社(2012)第123087号,20万字,2012。06. 三、特色教材 1.崔一喆,计红,范春玲,动物医学实验教程,中国农业出版社(2017)第243300,2018.01. |